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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4f3c53e3a498a8f325bb7e40d217d098065d94c6bd89c52990600264a2d7f6c' 
  AND token = 'AvgEtfgdH2kN4rsmmST/WwioOvXzoc46CLIESbhuz4o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}