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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc5a001295cf221634e0abfc4d2899e3f789fc737cf673a006e819982b350aee' 
  AND token = '/cgsC+m5CUCL5F0DYknhFRo5V08fVVvFOrKFVK0Pb+8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}