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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '901ca0436bccc027cc04e96acbd116df4f970f9c5c653ac5bc14c3ccd01b435f' 
  AND token = 'XTxF9bQ2gAsVsbR6JC0TFINfkUbGeqNXY5sCfKG3Dtw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}