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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4153ed7b5353db8614f6a7f7b8b5b197ceb8302b7096a9e368fa095c5e81eaa' 
  AND token = '06juelESu9CLDozEOCOUNguMnexUiTsZeB0rIoSip2g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}