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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '341a6aba15ba0ca515df518eae96afd3327aac1ddc0205c1a1bf36bd431f4d5b' 
  AND token = 'wrpUrZ1fgdVNGGtM9LjiWoD76E2Zid4ulE7sKZpsvv4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}