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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '124c549bf059ac2519e8c078bbce353a05def96b20862268d6c99872069134e1' 
  AND token = 'CM5ztvm+pOVE+St8Ure1x7TW4bWXLgNcy/LnQPRwn9w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}