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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5545f6a931c4a963a39f89017bd349a030142f6ac00d533dea4283db7368a8d' 
  AND token = '2hH9qUeS69KJeqFOQ60OkW4ZgjF4+CnDYmcP2ttJBJM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}