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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39b240ec1cac52d3664e88c90af6addddfa37defecd8a689a44dfb3fc647a0e4' 
  AND token = '8Zl43pC1XivQ78TtGHwQqaoGAuRUMJt/7wYX2Q3DjTY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}