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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '546c2200228ec8af6e88286fc1aaa8356e6a8a1cb0177a2c504e62f95651ffa1' 
  AND token = 'nBC0laypokaB4xpFQPW5gYWFs/qhO9oFeabr9dTBKJA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}