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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '918a1dce138a20e2378d4d687812a966716d4364adeb40c3345d26fd6fc8ce5a' 
  AND token = 'YO0LsUezDw0A+yXh99aTLDkNjzOEklLrUm2YBMdw1KI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}