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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f1533c0114a65753b4b622288d4510fd9a1b2e4f343e15119df84fe5a0daf5b' 
  AND token = 'Mpq70QVVcB+HEIVSse36rkxKoHd2v6lWYop8Tt+8lBs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}