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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e200d2d2d5e2af489c3964bbfa97f75c84b6ed3a5ab7d73af579c7d98f3c91c8' 
  AND token = '0LFT/Bz8KmZHoWO+2c7L5qRhcSM+HKDN5fb5cWEI4HA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}