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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '625aef4f5f338faf462b2729550c61c3665ffee62973166c82599e8f960bae57' 
  AND token = 'Zisnl8xElCDubEDflUI6n2PexIzXVzbRwnE5hiLw5N4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}