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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1f5ae32c11debf0b0617c1b13cc50d4831e5012c8b6ac76dffbfc4e47b8f2ca' 
  AND token = 'Bs2nnpodUTqNB2vg+79+NYSlLsKHiAdXkD9N8Veb3sY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}