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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ded509d2c9f36d5ff154feca9e207b153226a9d30dad57a42118d6df6eb22d22' 
  AND token = 'Enl68EHiMOG85oeNpe7oOHtnyjdt5RtLarAJIHCcEWY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}