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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2126b25608e7c11ee125e945b369c7d1250901047787cac3d14d1b57ff165eef' 
  AND token = '5HxBZEbPd3i4WlplVWFPrs0O3yofkPGR8ht8AAmR6ag=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}