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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed7d404f44b5373c3be43880b80d8913c8b0a2ffb2c9300da6e725bf879c08e7' 
  AND token = 'yzgf2LiGiQUs+rZDlhWdB8czfdv32uVtGGjQzgTGkaQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}