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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'efede20140a4a9dfff70c078e33a07737e68e826ed6eee3a084a86c14f458249' 
  AND token = 'LIkqA23RToWB8aGvQ7nLz42y/MEx0mru5eYWe87AW0c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}