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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9aeeba176eb8c41fe736cc3ed7b2242ca48343c96292f81735c4fcfa9aaf7556' 
  AND token = 'PUfjdhYc8I6VXK5EP7WSiTIzyb39LrLnNbFCkx+YFzg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}