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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd54553f95b45a6a2d0dee88bf69ff74bf541d357256f1def6dd80f53ae69cd9' 
  AND token = 'v35yo3BDGAx4x/nvCsx9DnnvrYQMHIsTq3dHSQe/0OY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}