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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a1f19a22696f7a97a4bdd28f413f19cfc71f6581fabac5e165df2b98a93e0a2' 
  AND token = 'km0ulBHHsAXANDee5ZVYQhMHE3SAIpo1f/pTCwx/+Kc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}