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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '08d80a9bc005e1b1e09970131ad33efdcd71d6ff76191b76dc582c994e6370f0' 
  AND token = 'XM6SbXUivdn1aOPNGZXe6DL5/KZ9lYBfyRbsVy2Qu9c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}