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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5fe5fc21b24848972b325807aa1c2d11b16f2d619e7225c00b2bb39c50330f5f' 
  AND token = 'pPaOUh+ZZaCKCGCG0onSaOBKPy/ToagLT7TY3090O2o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}