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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ce04c5ed2159b401eb31202e6e134a9af7d14a33e477234d0be3ee477a8677c' 
  AND token = 'U+HbJxS3Uq6H6CCN8bz07UUintajWPNlhCg+A5cZ0co=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}