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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a227c52e67e7c65c0d90718ae09dd3285b1ad63f05df907c02b5f8cb8d33dbc4' 
  AND token = 'DuClSRbtg9ARV6UjTelmFkSr/mEtJYPXdT3TVOfT+sk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}