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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '68dda3c08d30fd61e59362e04b888262718d4be3088a4b61fdc57ab96a834d1b' 
  AND token = 't1ufOT1LGY2bRUDD1PYf8EtYImwsDZGrpHv8Y9Qe2WE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}