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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48e681d356feed157b8d1a779118fcbeed52fc3327b0edec2102ff4b68af0879' 
  AND token = '9O2TAG/V/8pqqbYYBQBAdqINNPC8dH5yycoJ3ySExiQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}