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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '08afb3f74daf5a5d979fcd27440ec826961013ac0deb52cfe58cf400bbffb52d' 
  AND token = 'NP4msjuPJRc4GBhnVc+2hLfRl49xdYhXUQ3MwDcDc7E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}