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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d15cb7d141c6d4e71e202702e7d79d2169f5d6e748863be95abb55b58efb626' 
  AND token = 'FsM+1qYLzrEn2CzqaIXIA/M/sVvxs/jevdk+8ffDr0c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}