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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d882f62de92d56177fb8ef84866e41db289dcb6ff08e18b2d5d77ef265fd164' 
  AND token = 'Y9oyh3J60h2H6cwDrjU2BuT/vRepvAdH3KUsh8bnZm4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}