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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80cc9dabe12820fbce53b6779549a3f207bc12c51d5b5726cb06326f6c98b653' 
  AND token = 'QLyyYTAlnx3AwYVBQzYUGUxdMKcN9XMsUHC29kU+vKc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}