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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d21768d8079f7f5bd2800f17e62dd0506105b6d5c9f0a63f6b0fbe54338068d' 
  AND token = 'N46cOdE7Jd9xRpTjLasMmw+p+YEO/kAgTwY2YgV798U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}