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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8c7e741e4005e14cedf0f3bcea8e38e109292e49fe47f877a2f727176f9072b' 
  AND token = '1SGt8jmL8RdyPow27hVBoCRoCJPuDFoXHi1+sc4GZW4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}