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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0c8c2f97b35558e239401e0c809a995497bef9950eebdb13e9fd90917c65330' 
  AND token = 'icyEb/SlmxPO3WdeOIe6EoSifoJh8m7cfquFR8KoU0A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}