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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5865b800b9aefe29dbca799102afa5841fd1d66ac27060c02ac2eb9b55f7735d' 
  AND token = 'pgD3YIb4GHil3m0Wv2/ZA/YxOHYH4EGlJaoDkooskp4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}