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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6414427ae3d6db3a7a7192c4c3485cf86075712f5e35518075cbfe2244f36ca' 
  AND token = 'HAZvlVkFZnZWme3Ws6yaBcFOrWL2hh19v6b+qlZ6pt4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}