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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '482911751a91e9d97fb267b3bde7b7a6c700d65a358e84dcd80cee15ee99aa86' 
  AND token = 'GtUQx5h3WOejqg+cAcjWFQ7TSnQlYK7oDuhpP/5ip9Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}