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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f42bd879d2ad6284f3613f27dea41bee7a7a7ee8e61a3a224ef25b7a4efaddb6' 
  AND token = 'edemXLJLG+mPy4uLcZrJnXKSkuqspgsbUE7Sat1eagM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}