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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e8e00fcff28c3bb7e32bf6b5f1cc2ab6349ad9e7c1fe0c8311dd40d046ac41c' 
  AND token = 'Hu2msDOKc/faRLNxsrV2VGBvb0Im6p3jdkh4nUpsQVo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}