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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c7d3756378c424f6aefcfcd9c6c67f0a16dd1c96037089544ce801c93d31b77' 
  AND token = 'AEPu2kVNU5yoErCbmd2YOSncMdzB/vTOR8f4xLpO5iU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}