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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18b1d790b084c85994ff2515256f080a6cf0f3bf587f5d03869d3e64a8534edd' 
  AND token = 'uzIgXr8A/A2zN16o3l1TKeVcf4nu9HbiYENhhXZGsZM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}