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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10f0cf12ab5bf739dcebd322429818251f3b5b7edd3ee4be82f7087c9b3c2f54' 
  AND token = 'XndjrjUYyorGspf3wJWxfm6uSNGmb/nvvQO6WxxLw38=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}