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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9efce0283d64f1be0630032b9c1d6d9b8e32eebb5e2b1980a6f2d45f1b8496dc' 
  AND token = 'VFIhRNyzUTt9jMmyNa49yAw1npCkqt3X+S/YoTKtFlU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}