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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4afd58e7c5d3bdf60a74ad43713718b7e3706416adae899e03a3ffdfe84956bb' 
  AND token = '4/2tgNVcg+tykZbfwEejwOzX0PkrV+ii3eX9x2Ys8BU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}