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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4e6bbcdd231fa440bd38331e6ac46be648ade553a8ded2349da4ed0b72d1d95' 
  AND token = 'alppyU1qBDHmsmNuQQXM023/TsecN7PT5ZvGiDT+oPc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}