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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '437f1aed068004d6fe361d4067acd20aab2648d4ecd281cd4a1c5363179ac421' 
  AND token = 'fXpwuAI0/9LmyIPWM1wCV9R24Hxk8t9S5BZuQuYKCe4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}