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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '56b28f46e32b15293e25e27da01b51826df378938c9c84ff06ef2b08ee11d431' 
  AND token = 'tUq1VEDtLwRJr6+vs3QbAC5J4eKXm/cLxMp5NBqyXaI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}