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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a9355c15d95ded0f9f230dab38f9adf9d03a1183f7dadc1f8c157426fed272e' 
  AND token = '48Wa2gHHKGhNTinMeYJjznA2ygRK98xMBw10L1UkzWE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}