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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5ce2a5d29e4337e2c79ada961a65887335e6012ec5a569bbd4d9a575dd75bfc' 
  AND token = 'gcf+Ia3NdRYDMG2vCll3294q7Sl/lCsI57KJVQMaZUY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}