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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c09e1d222451d72ecd757ef0455ead6873de9dbb9030c0344ad71fa0f3246bdb' 
  AND token = 'pJFd7kA3WcfPFHiSA0s2H0uKKf/OqWuMsRgeK7Cjxn8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}